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LOS ANGELES (CBSLA.com) A fire destroyed a 7-story apartment building under construction and damaged two others early Monday morning in downtown.

The fire was reported around 1:20 a.m. at the 1.3-million-square-foot Da Vinci apartments, located at 906 N. Fremont Avenue, the Los Angeles Fire Department said.

More than 250 firefighters were dispatched to the scene, including crews from nearby Fire Station 3.

They literally opened the door to see an entire city block with fire showing, Cpt. Jamie Moore said.

Crews attacked the wood-burning fire, which could be seen from across the city, from the ground and the Harbor Freeway.

The collapse of scaffolding and the structures wooden frame forced the closure of northbound Harbor (110) Freeway to the northbound 101 Freeway until 10 a.m. The northbound 110 Freeway to the southbound 101 remained partially closed until further notice.

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More than two-thirds of that occupancy was on fire causing significant exposure issues to two nearby high-rise buildings, LAFD Chief Ralph Terrazas said.

A 15-story Los Angeles County Health Department building, located at 313 Figueroa Street, suffered radiant heat damage, while a 16-story high-rise at 221 Figueroa Street had active fire on three floors of that building and sprinkler activation on six floors, Chief Terrazas said.

Authorities closed the 221 Figueroa building for business Monday and established a help line at 1-800-882-1482.

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Fire Destroys Apartment Building Under Construction In Downtown LA

Huge Los Angeles fire closes freeways An apartment complex in downtown Los Angeles caught fire early Monday morning and has shut down parts of two major freeways in the city, according to the Los Angeles Times.

The complex was reportedly under construction at the time of the fire.

Transition lanes between the 110 and 101 freeways have been shutdown, the state highway patrol told the LA Times.

The fire can be seen for miles in the LA area.

No injuries have been reported so far. It's not yet clear what started the fire. The fire broke out shortly before 1:30 a.m. Pacific time, KTLA reports.

More than 200 firefighters are on scene, according to the LA Times.

Damian Dovarganes/AP Los Angeles County firefighters battle a fire at an apartment building under construction next to the Harbor CA-110 Freeway in Los Angeles, early Monday, Dec. 8, 2014. The building was not occupied, the Los Angeles Fire Department reported. (AP Photo/Damian Dovarganes)

Here are some photos and videos of the fire:

Incredible shot of a fire at an under construction apartment complex in Los Angeles pic.twitter.com/UmmiDNYHaR

#BREAKING: Apartment fire in DTLA shuts down the NB 110 transition to the NB 101 Freeway... pic.twitter.com/3zox9x73op

Link:
A Massive Apartment Fire In LA Has Shut Down 2 Major Freeways

COLUMBIA, Md., Dec. 9, 2014 /PRNewswire/ --ACell, Inc. today announced that a peer-reviewed study, "Esophageal Reinforcement with an Extracellular Scaffold During Total Gastrectomy for Gastric Cancer,"was published in theOctober, 2014 issue of Annals of Surgical Oncology, featuring its MatriStem Surgical Matrix PSM device.

The retrospective study compared the rate of anastomotic leaks after total gastrectomy in two patient groups one group that had esophageal reinforcement using MatriStem Surgical Matrix PSM and a second group as a control. 2.7% of patients in the MatriStem group had a postoperative leak, compared to 12% in the control group a reduction of more than 75%.

"Post-operative leaks are a potentially devastating complication of esophageal reinforcement, with morbidity rates approaching 50%," said Thomas Gilbert, Ph.D., Vice President of Research and Development at ACell. "Various approaches have been developed and tried with the hopes of reducing the occurrence of post-operative leaks, but none have been widely accepted by the clinical community."

Post-operative leaks can also increase the incidence of strictures (narrowing of the esophagus) and have a negative impact on the patient's nutritional status.

Gastrectomy is a surgical procedure that removes a patient's stomach; typically the surgeon then connects the esophagus directly to the small bowel with a procedure called anastomosis. A full or partial gastrectomy is usually the only curative measure for patients with primary stomach cancer, which affects more than 20,000 Americans each year.

"The research presented is very promising and could represent a significant step forward in treating stomach cancer patients who have undergone total gastrectomy," said Gilbert. "We have initiated a prospective study with the same research team to further examine the potential for MatriStem technology to improve outcomes after esophageal anastomosis, which we believe will validate these initial promising results and lead to broader adoption of the technique."

About ACell, Inc.

ACell, Inc. is a leading regenerative medicine company focused on the development, manufacturing and commercialization of unique extracellular matrix (ECM) products to facilitate the repair and remodeling of damaged tissues. ACell is committed to becoming and remaining an innovative leader in regenerative medical technology, offering superior healing options for doctors and patients. ACell is a privately held company and operates manufacturing facilities in Columbia, MD and Lafayette, IN. For more information, call (800) 826-2926 or visit http://www.acell.com.

About MatriStem

MatriStem products are porcine-derived extracellular matrices (ECMs) that contain the epithelial basement membrane from porcine urinary bladder matrix (UBM). UBM is a layer of tissue that facilitates a constructive tissue remodeling response by the patient's body. MatriStem products are indicated for use in general surgery, gynecological surgery, and in the management of a wide range of wounds. Refer to the IFU supplied with each device for indications, contraindications and precautions. All MatriStem devices are made in the USA.

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MatriStem Featured in Annals of Clinical Oncology

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