Study Sheds Light on Marijuana and Paranoia

By Peter Russell WebMD Health News

Reviewed by Rob Hicks, MD

July 17, 2014 -- An in-depth investigation has concluded that people who smokemarijuanaare much more likely to have paranoia than people who don't use the drug.

The study also identifies psychological factors that can lead to feelings of paranoia in people exposed to the main psychoactive ingredient in marijuana, THC.

The team of researchers, led by Professor Daniel Freeman, PHD, of the University of Oxford, found that worrying, low self-esteem,anxiety,depression,and having a range of unsettling changes in perceptions most likely lead to the feelings of paranoia.

A paranoid person is someone who has an unfounded fear that others intend to harm them. Many people have some degree of paranoia. Those who are young, poor, in bad health, contemplating suicide, or using marijuana (also called cannabis) are more prone to have paranoid episodes.

The scientists set out to explore two things:

They tested 121 participants between the ages of 21 and 50. All of them had taken marijuana at least once before.

None of the participants had a history ofmental illness, and all were screened to rule out relevant health conditions. But all of those taking part said they'd felt paranoid at least once in the previous month.

The volunteers were not invited to smoke joints. Instead, the scientists injected some of them with THC in order to ensure the results were as accurate as possible.

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Study Sheds Light on Marijuana and Paranoia