Minecraft let #39;s play part 5 Remodeling
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303-472-1511 Van Dyk Home Remodeling After wood deck repair
remodel-in-denver.com 303-472-1511 The deck is now completed and looking great! Denver has many sunny days even in the fall and winter. This is a great place to have a lunch or just enjoy the out door on a new wood deck.From:HomeRemodeling303Views:0 0ratingsTime:01:34More inEducation

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Van Dyk Home Remodeling wooden deck project Oct 2012
remodel-in-denver.com 303-472-1511 Learn how our construction team can fix, build or repair your home or deck. Van Dyk Home remodeling has skilled carpenters and construction workers that can build you a dream deck, kitchen, room addition and more.From:HomeRemodeling303Views:0 0ratingsTime:02:29More inTravel Events

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IBM visuals of Inaugration of 19.0 lakhs GHMC works in Azampura Division.avi
Inauguration of Rs/ 19.0 lakhs of GHMC work in Azampura division by Amjed Ullah Khan (Corporator) Azampura Division On 1st Dec 2012 at 4:00 PM. 1)Laying of BT Road from Gulzar Masjid to Anjuman E Mehdavia, Chanchalguda (Amount Rs/ 5.0 lakh s) 2)Lying of CC Road from Qader Khan Dairy to main road Chanchalguda. (Amount Rs/ 4.75) 3)Remodeling of SW Drain and laying of CC Road from Aizza School (front Gate) to new road Chanchalguda. (Amount Rs/ 9.70 lakhs)From:MBTHydViews:6 0ratingsTime:08:52More inNews Politics

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Van Dyk Home Remodeling wood deck repairs after construction 303-472-1511
remodel-in-denver.com 303-472-1511 More video of a recently completed wooden deck repair in Highlands Ranch Colorado. Denver has many sunny days and having a wood deck out doors increases your living space for your home. Give us a call for your next home remodeling project.From:HomeRemodeling303Views:0 0ratingsTime:02:17More inPeople Blogs

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Inaugration of GHMC works,Amount Rs/ 19.0 lakhs in Chanchalguda under Azampura Div .mpg
Inauguration of Rs/ 19.0 lakhs of GHMC work in Azampura division by Amjed Ullah Khan (Corporator) Azampura Division On 1st Dec 2012 at 4:00 PM. 1)Laying of BT Road from Gulzar Masjid to Anjuman E Mehdavia, Chanchalguda (Amount Rs/ 5.0 lakh s) 2)Lying of CC Road from Qader Khan Dairy to main road Chanchalguda. (Amount Rs/ 4.75) 3)Remodeling of SW Drain and laying of CC Road from Aizza School (front Gate) to new road Chanchalguda. (Amount Rs/ 9.70 lakhs)From:MBTHydViews:1 0ratingsTime:14:49More inNews Politics

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Office space for rent in Mount Pleasant, Racine WI
Office space for rent in Mount Pleasant, Racine WI. American Building, 5605 Washington Ave, Hwy 31 and Hwy 20, Next to new Walmart Remodeling to suit tenants needs. Modified gross lease terms. Great signage. Ample fee parking. Call Tom for a showing 262-835-1767.www.loopnet.comFrom:tpotiskViews:0 0ratingsTime:02:41More inNews Politics

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Originally published November 30, 2012 at 8:01 PM | Page modified December 1, 2012 at 8:47 AM

Kitchen and bathroom renovations top the list of improvements for increasing the value of a home. But this labor-intensive remodeling can get expensive. Even without changing room layouts, the simple job of replacing finishes and fixtures can cost more than the price of a new car.

What builders call pull and replace remodeling can run about $12,000 to $22,000 for the average 5- by 7-foot bathroom and $29,000 to $52,000 for a 12- by 12-foot kitchen, estimates Rick Matus of Bethesda-based Case Design/Remodeling. As soon as you start moving plumbing, electrical wiring and walls, the costs go up substantially from there, he says.

Budget-minded homeowners are finding cheaper solutions in the $10,000 to $20,000 range by making do with existing appliances and fixtures, refinishing kitchen cabinets and shopping for bargains. Suppliers and builders, in turn, are responding to the recession-driven demand for cost-conscious kitchen and bath remodeling with package deals aimed at guaranteeing the costs of materials and labor.

At first, there was no way I was going to spend $18,000 to $25,000 to remodel a bathroom, says Vienna homeowner Hannah Laufe, an attorney. But to get what we wanted, my research showed that was the amount we needed to spend.

Laufe and husband Richard Miller, a teacher, decided to renovate the outdated and worn master bathroom in their 1960s rambler. Everything was pink, the medicine cabinet was rusty and the faucets didnt work as well as they should, Laufe says.

The couple tapped Case to remodel the space based on the firms new renovation program, called the 2012 Bath Collection, launched in January. For $13,000 to $25,000, the company will demolish an existing space, remove lead paint if necessary, and install backer board and tile. New plumbing fixtures, vanity, towel bars, lighting and painting are included in the price. It saves the headache of shopping different sources, Matus says. He says Case is now considering similar package deals for kitchens.

Laufe and Miller had a choice of designs in contemporary, traditional and transitional styles, but within a narrow range of products. They chose a stained maple vanity with a granite countertop, a glass door for the shower, and marble-look-alike porcelain tile on the floor and shower stall, spending about $20,000 on the project. It took less than two weeks to complete, Laufe says.

Management consultant Cope Willis and wife Sophie, who works for an educational software company, spent about $9,000 to partially remodel their pink bathroom. They kept the existing toilet and pedestal sink, and hired a local handyman to install a new bathtub and finishes. We worked within the existing constraints of the bathroom to keep costs down, Cope Willis says.

New subway-style tile around the tub, marble tiles on the floor and beadboard wainscoting create what Willis calls a clean, traditional look in keeping with the architectural character of the couples 1938 Colonial in upper Northwest Washington.

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Savvy homeowners find ways to cut remodeling costs

ScienceDaily (Nov. 29, 2012) Chromatin remodeling -- the packaging and unpackaging of genomic DNA and its associated proteins -- regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell death as well as cell fate. In their latest study, scientists at the Stowers Institute for Medical Research are continuing to unravel the finicky details of how these architectural alterations are controlled.

Through a series of biochemical experiments, Stowers Investigators Ron Conaway, Ph.D., and Joan Conaway, Ph.D., and their team discovered that chromatin remodeling enzyme and suspected oncogene ALC1 (short for Amplified in Liver Cancer 1) is activated through an unusual mechanism: Its shape shifts in the presence of its activators. Their finding identifies a new instrument in cells' molecular repertoire of chromatin-remodeling tools and a potential cancer therapeutic target.

One of the main tasks of chromatin remodeling enzymes, Ron Conaway explains, is "to make DNA accessible so events like repair and gene transcription can occur." Postdoctoral research associate and first author Aaron Gottschalk, Ph.D., previously figured out that ALC1 required protein partners to activate its remodeling function. Publishing in an upcoming issue of the Journal of Biological Chemistry, he dissects the mechanism by which this occurs.

ALC1 and its ilk have a common protein domain, SNF2, that uses the energy of ATP hydrolysis to move nucleosomes -- the basic repeating units of chromatin -- around, in a process called nucleosome sliding.

"I was intrigued because ALC1 has a unique macrodomain not found on any other SNF2 family member," Gottschalk says. His interest was further piqued when he found that while most ATP-dependent chromatin remodelers function as large multi-protein complexes, ALC1 appeared to work by itself. At the same time, where most of its group-happy family members readily demonstrated nucleosome sliding activity in vitro, ALC1 was not only a lone ranger but also "completely dead on its own."

Gottschalk deduced that ALC1 may function independently, but it needs a boost from a couple of sidekicks: PARP1, an enzyme that responds to several kinds of DNA damage; and NAD+, the substrate by which PARP1 transfers chains of poly (ADP-ribose) onto itself and other target proteins, in a process called PARylation.

Only when PARP1 and NAD+ are on the scene does ALC1 spring into action, altering the accessibility of DNA by shifting nucleosomes around. Gottschalk's earlier findings were published in the Proceedings of the National Academy of Sciences in June 2009.

"We then extended this research," Conaway says, "and the upshot of our recent JBC paper is that ALC1 is likely activated through a series of physical interactions. ALC1's unique macrodomain can bind PAR, and protein-protein interactions also occur between ALC1 and PARP1." Gottschalk and coauthor Rushi Trivedi, a graduate student in the Biochemistry & Molecular Biology department at KU Medical Center, developed a novel footprinting assay that enabled this observation. Rather than merely activating ALC1 and moving on, the researchers found that the trio of PARP1, NAD+ and ALC1 hangs out in a stable complex.

"So PARylated PARP1 and NAD+ are allosteric effectors -- by binding to ALC1, they alter its state from dormant to active," Conaway says. "It's an interesting mechanism that's different from how most other chromatin remodelers work. It may also help explain other evidence that PARP1 has the ability to rearrange nucleosomes and reorganize chromatin; this could be one way by which PARP1 exerts its influence."

Apart from its role in modifying chromatin structure, not much is currently known about ALC1. It's regarded as a possible oncogene, being found in excess in hepatocellular carcinoma cells and because overexpression of ALC1 in mice induces spontaneous tumors.

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Chromatin remodeling: Activating ACL1 with a little help from 'friends'

HDR Remodeling, a remodeling contractor in the East Bay, recently received two awards during the annual "Remmie" Awards Dinner on Nov. 14.

Berkeley, CA (PRWEB) November 28, 2012

"The Bay Area is home to some of the most talented design and construction professionals in the country. We are proud that our company has been recognized for excellence from a field of such talented individuals and highly professional companies," Jim Tibbs, creative director of HDR Remodeling, said.

The Remmie Awards are judged by a team of four industry-leading professionals who select the winning projects based on creative problem solving, functional and aesthetic enhancements, craftsmanship, and innovative use of materials. The two winning kitchen designs from HDR Remodeling were completed in-house by Jim Tibbs and Lucy Chia Lu Kuo, designer, and executed under the management of Philip and Anderson and Brian MacRae, president and production manager of HDR Remodeling. HDR Remodelings two projects will be entered into the national competition, which is held in early 2013.

The San Francisco Bay Area chapter of NARI includes the cities of San Francisco, Berkeley, Oakland, Piedmont and the surrounding East Bay cities, as well as the North Bay up to and including Santa Rosa.

The competition within the Bay Area remodeling industry is fierce, based on the large number of very talented professionals and outstanding companies that operate in this area. For this reason, it is a major honor for a company to be singled out for an award. It is also a great way for the general public to be introduced to the work of the local leaders in the industry.

The mission of the San Francisco Bay Area chapter of NARI is to build an interactive community of general contractors, trade contractors, specialty contractors, designers, suppliers and affiliated professionals within the remodeling industry.

For more information about any of HDR Remodelings services, call 510-984-3755 or visit the home remodeling companys website at http://www.hdrremodeling-eastbay.com. HDR Remodeling's office is located at 2952 Sacramento St. in Berkeley.

About HDR Remodeling

HDR Remodeling is dedicated to providing clients with personalized remodeling services to give them healthier and more beautiful living spaces at reasonable budgets. The company is certified with Build It Green as a remodeling contractor and has also been awarded "Green Check" by the Sierra Club Green Home Initiative. HDR Remodeling designs and transforms homes to improve the comfort of clients while integrating green building practices.

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East Bay Home Remodeling Company HDR Remodeling Received Awards at "Remmie" Awards Dinner